AV457

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T204285-10mg	10 mg	-	-	-	7 - 10 business days*		-
TGM-T204285-50mg	50 mg	-	-	-	7 - 10 business days*		-

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Description: AV457 is a potent and selective inhibitor of mTOR. It effectively suppresses cyst... more

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Product information "AV457"

Description: AV457 is a potent and selective inhibitor of mTOR. It effectively suppresses cyst growth in polycystic kidney disease (PKD) organoids. AV457 reduces the protein expression of P-s6 and P-p70s6, but it does not decrease the protein expression of P-AKT. Target: mTOR. Smiles: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)NS(=O)(=O)CCOCCOC

Supplier:	TargetMol
Supplier-Nr:	T204285

Properties

MW:	1065.36 D
Formula:	C55H88N2O16S

Database Information

Handling & Safety

Storage:	+4°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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