Asiaticoside B

Asiaticoside B is a triterpenoid glycoside that has been found in A. asiatica and has anticancer activity. It is cytotoxic to HepG2 and MCF-7 cancer cells with IC50 values of 9.74 and 8.32 µM, respectively.Formal Name: (2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-olean-12-en-28-oic acid, O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl ester. CAS Number: 125265-68-1. Synonyms: Terminoloside. Molecular Formula: C48H78O20. Formula Weight: 975.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 15 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)O)O)O[C@H]1OC[C@H]([C@H]([C@@H]([C@H]3O)O)O)O[C@H]3OC([C@]45[C@](CC(C)(CC5)C)([H])C6=CC[C@@]([C@@]7([C@@]([C@@](C)([C@H]([C@@H](C7)O)O)CO)([H])[C@@H](C8)O)C)([H])[C@]8(C)[C@@]6(CC4)C)=O. InChi Code: InChI=1S/C48H78O20/c1-20-28(53)30(55)33(58)40(64-20)67-36-25(17-49)65-39(35(60)32(36)57)63-18-26-29(54)31(56)34(59)41(66-26)68-42(62)48-12-10-43(2,3)14-22(48)21-8-9-27-44(4)15-24(52)38(61)45(5,19-50)37(44)23(51)16-47(27,7)46(21,6)11-13-48/h8,20,22-41,49-61H,9-19H2,1-7H3/t20-,22-,23+,24+,25+,26+,27+,28-,29+,30+,31-,32+,33+,34+,35+,36+,37+,38-,39+,40-,41-,44+,45-,46+,47+,48-/m0/s1. InChi Key: NNWMHSNRRWMMBI-PJISEHJASA-N. Origin: Plant/Centella asiatica.