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Description: AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM, Ki: 0.6 nM) with demonstrated selectivity for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis: 89.7 nM, 490 nM, 6.6 nM, and 98.5 nM, respectively). Target: 5-HT Receptor. Smiles: CN(C)[C@H]1CCc2c(C1)cccc2-c1c(C)nn(C)c1C. References: Perez-García GS, et al. Effects of the potential 5-HT7 receptor agonist AS 19 in an autoshaping learning task. Behav Brain Res. 2005 Aug 30,163(1):136-40.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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