Arctiin

Arctiin is the major active lignin in fruits of the burdock plant A. lappa. It demonstrates potent antiviral activity against influenza A virus and anti-inflammatory effects by decreasing the production of nitric oxide and pro-inflammatory cytokines. Arctiin is metabolized by human intestinal bacteria into various bioactive metabolites including arctigenin (Cay-14913) and enterolactone (Cay-10112), which respectively exhibit growth inhibitory and growth promoting activity in MCF-7 breast cancer cells at 10 µM.Formal Name: (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[[4-(beta-D-glucopyranosyloxy)-3-methoxyphenyl]methyl]dihydro-2(3H)-furanone. CAS Number: 20362-31-6. Synonyms: Arctigenin-4-Glucoside, NSC 315527. Molecular Formula: C27H34O11. Formula Weight: 534.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, Ethanol: 2 mg/ml. lambdamax: 229, 280 nm. SMILES: COC1=C(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)C=CC(C[C@H]([C@@H](CC3=CC(OC)=C(OC)C=C3)CO4)C4=O)=C1. InChi Code: InChI=1S/C27H34O11/c1-33-18-6-4-14(10-20(18)34-2)8-16-13-36-26(32)17(16)9-15-5-7-19(21(11-15)35-3)37-27-25(31)24(30)23(29)22(12-28)38-27/h4-7,10-11,16-17,22-25,27-31H,8-9,12-13H2,1-3H3/t16-,17+,22+,23+,24-,25+,27+/m0/s1. InChi Key: XOJVHLIYNSOZOO-SWOBOCGESA-N.