APX-115 free base

Item number	Size	Delivery time	Price
TGM-T10353-1mg	1 mg	7 - 10 business days*	52.00€
TGM-T10353-5mg	5 mg	7 - 10 business days*	120.00€
TGM-T10353-1mL	1 ml	7 - 10 business days*	125.00€
TGM-T10353-10mg	10 mg	7 - 10 business days*	198.00€
TGM-T10353-25mg	25 mg	7 - 10 business days*	395.00€
TGM-T10353-50mg	50 mg	7 - 10 business days*	594.00€
TGM-T10353-100mg	100 mg	7 - 10 business days*	864.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Description: APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH... more

Close menu

Product information "APX-115 free base"

Description: APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with inhibition constants (Kis) of 1.08 µM, 0.57 µM, and 0.63 µM for Nox1, Nox2, and Nox4, respectively, and it effectively prevents kidney injury. Target: NADPH-oxidase, NADPH. Smiles: CCCc1c(O)n(nc1-c1ccccc1)-c1ccccn1. References: Kwon G, et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 2017 Jun 16,8(43):74217-74232.

Keywords:	Ewha-18278 free base
Supplier:	TargetMol
Supplier-Nr:	T10353

Properties

MW:	279.34 D
Formula:	C17H17N3O

Database Information

CAS :

1270084-92-8| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

Information about the product reference will follow. more

Close menu

You will get a certificate here

Go back

Read, write and discuss reviews... more

Close menu

Customer review for "APX-115 free base"

Write a review