Antifibrotic agent 1

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T207178-10mg	10 mg	-	-	-	7 - 10 business days*		-
TGM-T207178-50mg	50 mg	-	-	-	7 - 10 business days*		-

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Description: Antifibrotic agent 1 is an orally active medication designed to treat idiopathic... more

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Product information "Antifibrotic agent 1"

Description: Antifibrotic agent 1 is an orally active medication designed to treat idiopathic pulmonary fibrosis (IPF). It effectively mitigates IPF-related processes, including TGF-beta-induced epithelial-mesenchymal transition (EMT) and fibroblast-to-myofibroblast transition (FMT), as well as profibrotic M2 polarization. Antifibrotic agent 1 selectively inhibits CSF-1R, PDGFR-alpha, and Src family kinases (SFKs), while sparing VEGFR, FGFR, and Abl to minimize off-target toxicity. In a bleomycin (BLM)-induced pulmonary fibrosis mouse model, it demonstrates strong antifibrotic activity. Target: c-Fms, PDGFR, Others, Src

Supplier:	TargetMol
Supplier-Nr:	T207178

Properties

Formula:

C27H23ClN6O2

Database Information

Handling & Safety

Storage:	+4°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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