AMZ30
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
A covalent inhibitor of PME-1 (IC50 = 0.6 µM), reduces the levels of methylated PP2A in HEK293T... more
Product information "AMZ30"
A covalent inhibitor of PME-1 (IC50 = 0.6 µM), reduces the levels of methylated PP2A in HEK293T cells stably overexpressing PME-1 at 20 µM. AMZ30, inhibits t-BHP-induced decreases in U87MG and U-251MG cells at 210 µM. Formulation: A crystalline solid. InChI: InChI=1S/C19H12FN3O6S2/c20-14-6-8-17(9-7-14)30(26,27)19(13-21)11-15-4-2-10-22(15)31(28,29)18-5-1-3-16(12-18)23(24)25/h1-12H/b19-11+. InChIKey: GUCUORSUHTZMBW-YBFXNURJSA-N. SMILES: O=S(C1=CC([N+]([O-])=O)=CC=C1)(N2C=CC=C2/C=C(S(C3=CC=C(F)C=C3)(=O)=O)\C#N)=O
| Keywords: | ML-136, (2E)-2-[(4-fluorophenyl)sulfonyl]-3-[1-[(3-nitrophenyl)sulfonyl]-1H-pyrrol-2-yl]-2-propenenitrile |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 42052 |
Properties
| Application: | Protein phosphatase methylesterase 1 (PME-1, PPME1) covalent inhibitor |
| Immunogen: | 461.45 |
| MW: | 461.45 D |
| Formula: | C19H12FN3O6S2 |
| Purity: | >98% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 1313613-09-0| Matching products |
| KEGG ID : | K13617 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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