Amthamine (hydrobromide)

Amthamine is a histamine H2 receptor agonist (pD2 = 6.21 in isolated guinea pig atria). It is selective for H2 over H3 receptors (pD2 = 4.7 in isolated guinea pig ileum). Amthamine increases heart rate in spontaneously beating isolated guinea pig atria (pD2 = 6.72) and decreases contractions induced by cholecystokinin (CCK) octapeptide in a dose-dependent manner in isolated guinea pig gallbladder strips. It increases sheep red blood cell-induced production of IgG and IgM antibodies in rabbit serum when administered at a dose of 10 µg/kg twice per day.Formal Name: 2-amino-4-methyl-5-thiazoleethanamine, dihydrobromide. CAS Number: 142457-00-9. Molecular Formula: C6H11N3S . 2HBr. Formula Weight: 319.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Water: soluble. lambdamax: 264 nm. SMILES: NC1=NC(C)=C(CCN)S1.Br.Br. InChi Code: InChI=1S/C6H11N3S.2BrH/c1-4-5(2-3-7)10-6(8)9-4,,/h2-3,7H2,1H3,(H2,8,9),2*1H. InChi Key: XFXNNOPUDSFVJE-UHFFFAOYSA-N.