Amphotericin B (Fungizone) USP (Streptomyces)

Amphotericin B (Fungizone) USP (Streptomyces)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2220.1 1 g - -

3 - 19 business days*

104.00€
A2220.10 10 g - -

3 - 19 business days*

326.00€
A2220.25 25 g - -

3 - 19 business days*

624.00€
A2220.100 100 g - -

3 - 19 business days*

1,379.00€
 
Amphotericin B is a polyene antifungal agent for yeast, mold and mycoplasma. It was first... more
Product information "Amphotericin B (Fungizone) USP (Streptomyces)"
Amphotericin B is a polyene antifungal agent for yeast, mold and mycoplasma. It was first isolated by Gold, et a., from Streptomyces nodosus in 1955. It is an amphoteric compound composed of a hydrophilic polyhydroxyl chain along one side and a lipophilic polyene hydrocarbon chain on the other. Amphotericin B is poorly soluble in water. Amphotericin B binds to sterols, preferentially to the primary fungal cell membrane sterol, ergosterol. This binding disrupts osmotic integrity of the fungal membrane, resulting in leakage of intracellular potassium, magnesium, sugars, and metabolites and then cellular death. Used in the preparation of baculoviral stocks. , Synonyms:, Abelcet, Abelecet, AmBisome, Ampho-Moronal, Amphocin, Amphozone, Apothecon, Fungilin, Fungizona, Fungizone, Halizon, LNS-AmB, NS 718, NSC 527017, CAS Number: 1397-89-3, Molecular Formula: C47H73NO17, Molecular Weight: 924.09, Appearance: Supplied as a yellow to orange powder. Identification (FAB/MS): Conforms to reference, Solubility: Soluble in DMSO and DMF/HCl, Amphotericin B is poorly soluble in water. Potency: >750ug Amphotericin B/mg, Loss on Drying: <5%, Residue upon Ignition: <0.5%, Endotoxin: <2Eu/mg, Storage: Store at 4°C. Light sensitive., , Meets or exceeds USP specifications.
Supplier: United States Biological
Supplier-Nr: A2220

Properties

MW: 924.09 D
Formula: C47H73NO17
Format: Cell Culture Grade

Database Information

CAS : 1397-89-3| Find alternatives

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
Caution
Our products are for laboratory research use only: Not for administration to humans!
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