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AMCA is fluorescent protein labeling agent. It contains an N-hydroxysuccinimide ester that reacts with lysine residues to form photostable amide links. Upon activation with UV light, AMCA displays emission maxima of 400-460 nm. It has commonly been used in multiplex immunophenotyping applications.Formal Name: 7-amino-4-methyl-2-oxo-2H-1-benzopyran-3-acetic acid. CAS Number: 106562-32-7. Synonyms: AMCA blue, 7-Amino-4-methyl-3-coumarinylacetic Acid, 7-Amino-4-methylcoumarin-3-acetic Acid. Molecular Formula: C12H11NO4. Formula Weight: 233.2. Purity: >90%. Emission: 400-460 nm. Formulation: (Request formulation change), A solid. Solubility: DMF: 2mg/mL, DMSO: 3mg/mL, DMSO:PBS (pH 7.2) (1:6): 0.14mg/mL. lambdamax: 234, 354 nm. SMILES: NC1=CC=C2C(OC(C(CC(O)=O)=C2C)=O)=C1. InChi Code: InChI=1S/C12H11NO4/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4H,5,13H2,1H3,(H,14,15). InChi Key: QEQDLKUMPUDNPG-UHFFFAOYSA-N.
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