Allicin

Description: Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth muscle cells' proliferation and migration induced by insulin, which may be related to the inhibition of the activation of ERK signal path. Allicin is beneficial in reducing blood cholesterol, triglycerides levels and systolic blood pressure in hypercholesterolemic rats, it may beneficially affect two risk factors for atherosclerosis-hyperlipidemia and hypertension. Target: IkappaB/IKK, Caspase, Antifection, p38 MAPK, TNF, ERK, ROS, IL Receptor, Others. Smiles: O=S(SCC=C)CC=C. References: Kourounakis PN, Rekka EA. Res Commun Chem Pathol Pharmacol. 1991 Nov,74(2):249-52.