Adezmapimod
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Adezmapimod (SB 203580) is a selective, ATP-competitive p38 MAPK inhibitor... more
Product information "Adezmapimod"
Description: Adezmapimod (SB 203580) is a selective, ATP-competitive p38 MAPK inhibitor (IC50=0.3-0.5 µM) that activates autophagy and mitochondrial autophagy, with more than 100-fold higher selectivity over PKB, LCK, and GSK-3beta. Target: Autophagy, p38 MAPK, Mitophagy. Smiles: FC1=CC=C(C2=C(N=C(N2)C3=CC=C(S(C)=O)C=C3)C=4C=CN=CC4)C=C1. References: Henklova P, et al. SB203580, a pharmacological inhibitor of p38 MAP kinase transduction pathway activates ERK and JNK MAP kinases in primary cultures of human hepatocytes. Eur J Pharmacol. 2008 Sep 28,593(1-3):16-23.
| Keywords: | SB203580, PB 203580, RWJ 64809 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1764 |
Properties
| Application: | p38 MAP kinase inhibitor |
| MW: | 377.43 D |
| Formula: | C21H16FN3OS |
Database Information
| CAS : | 152121-47-6| Matching products |
| KEGG ID : | K04368 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H318 |
| P Phrases: | P264, P270, P280, P301+310, P305+351+338, P310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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