Adenosine 5'-diphosphate (potassium salt hydrate)

Adenosine 5'-diphosphate (ADP) is an adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5' position. It is produced by dephosphorylation of adenosine 5'-triphosphate (ATP, Cay-14498) by ATPases and can be converted back to ATP by ATP synthases. ADP can also be metabolized to adenosine 5'-monophosphate (AMP, Cay-21094) and 2'-deoxyadenosine 5'-diphosphate (dADP). ADP can modulate several receptors, activating certain purinergic receptors (EC50 = 24 nM for P2Y1) and inhibiting others (IC50 = 67 nM for P2X2/3), inhibiting rat ecto-5'nucleotidase (Ki = 0.91 nM), and regulating the phosphorylation status of AMP-activated protein kinase (AMPK).Formal Name: adenosine 5'-(trihydrogen diphosphate), monopotassium salt, hydrate. Synonyms: Adenosine Pyrophosphate, ADP, 5'-ADP. Molecular Formula: C10H15N5O10P2 . K [XH2O]. Formula Weight: 466.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 257 nm. SMILES: O[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](COP(OP(O)(O)=O)(O)=O)[C@H]1O.[K].O. InChi Code: InChI=1S/C10H15N5O10P2.K.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20,,/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20),,1H2/t4-,6-,7-,10-,,/m1../s1. InChi Key: WKYJXLSNACHKHX-IDIVVRGQSA-N.