Adavivint

Item number	Size	Delivery time	Price
TGM-T5636-1mg	1 mg	7 - 10 business days*	42.00€
TGM-T5636-5mg	5 mg	7 - 10 business days*	84.00€
TGM-T5636-1mL	1 ml	7 - 10 business days*	98.00€
TGM-T5636-10mg	10 mg	7 - 10 business days*	125.00€
TGM-T5636-25mg	25 mg	7 - 10 business days*	206.00€
TGM-T5636-50mg	50 mg	7 - 10 business days*	367.00€
TGM-T5636-100mg	100 mg	7 - 10 business days*	549.00€

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Description: Adavivint (SM04690) is a selective inhibitor of the typical Wnt signaling pathway.... more

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Product information "Adavivint"

Description: Adavivint (SM04690) is a selective inhibitor of the typical Wnt signaling pathway. In SW480 cells, EC50=19.5 nM was measured using high-throughput TCF/LEF reporter gene experiments. Target: Wnt/beta-catenin. Smiles: CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4cncc(-c5cccc(F)c5)c4[nH]3)c2c1. References: Yazici Y , Mcalindon T E , Fleischmann R , et al. A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study[J]. Osteoarthritis & Cartilage, 2017, 25(10):1598.

Keywords:	Adavivint (SM04690)
Supplier:	TargetMol
Supplier-Nr:	T5636

Properties

Application:	Targets dual specificity protein kinase CLK2/3 [EC:2.7.12.1] (CLK2_3)
MW:	505.55 D
Formula:	C29H24FN7O
Format:	32160405

Database Information

CAS :	1467093-03-3\| Matching products
KEGG ID :	K08823 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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