Abemaciclib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with... more
Product information "Abemaciclib"
Description: Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity. Abemaciclib has antitumor activity and is used to treat advanced or metastatic breast cancer. Target: CDK. Smiles: C(C)(C)N1C=2C(=C(F)C=C(C2)C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=N4)=NC=C3F)N=C1C. References: Ku BM, et al. The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma. Oncotarget. 2016 Mar 22,7(12):14803-13.
| Keywords: | LY2835219, CDK4/6 dual inhibitor |
| Supplier: | TargetMol |
| Supplier-Nr: | T2381 |
Properties
| MW: | 506.59 D |
| Formula: | C27H32F2N8 |
Database Information
| CAS : | 1231929-97-7| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H360, H373, H410 |
| P Phrases: | P201, P202, P260, P273, P280, P314, P391, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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