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A2793 is an inhibitor of the two-pore domain potassium channel K2P18.1/TRESK (IC50 = 6.8 µM in ionomycin-stimulated Xenopus oocytes expressing the mouse receptor). It is selective for K2P18.1/TRESK over K2P2.1/TREK1, K2P10.1/TREK2, K2P4.1/TRAAK, K2P3.2/TASK2, K2P3.3/TASK3, K2P16.1/TALK1, and K2P13.1/THIK1 at 100 µM but does inhibit K2P3.1/TASK1.Formal Name: 2-[(5-chloro-8-quinolinyl)oxy]-acetic acid, ethyl ester. CAS Number: 88349-90-0. Molecular Formula: C13H12ClNO3. Formula Weight: 265.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Ethanol: Slightly soluble: 0.1-1 mg/ml. SMILES: ClC(C1=C2N=CC=C1)=CC=C2OCC(OCC)=O. InChi Code: InChI=1S/C13H12ClNO3/c1-2-17-12(16)8-18-11-6-5-10(14)9-4-3-7-15-13(9)11/h3-7H,2,8H2,1H3. InChi Key: JEMXUSHXYOXNFL-UHFFFAOYSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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