A-196
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Larger quantity required? Request bulk
Description: A-196 is a potent and selective inhibitor of SUV420h1 and SUV420h2, with IC50 values... more
Product information "A-196"
Description: A-196 is a potent and selective inhibitor of SUV420h1 and SUV420h2, with IC50 values of 0.025 µM and 0.144 µM, respectively, it is more than 100-fold selective over other histone methyltransferases and non-epigenetic targets. Target: Histone Methyltransferase. Smiles: Clc1cc2c(NC3CCCC3)nnc(-c3ccncc3)c2cc1Cl. References: Bromberg KD,etal.The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity.Nat Chem Biol. 2017 Mar,13(3):317-324.
| Keywords: | A 196 |
| Supplier: | TargetMol |
| Supplier-Nr: | T4343 |
Properties
| Application: | SUV420H1 & SUV420H2 inhibitor |
| MW: | 359.25 D |
| Formula: | C18H16Cl2N4 |
Database Information
| CAS : | 1982372-88-2| Matching products |
| KEGG ID : | K11429 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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