A 1070722
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: A 1070722 is a potent and selective GSK-3 inhibitor, exhibiting high affinity for... more
Product information "A 1070722"
Description: A 1070722 is a potent and selective GSK-3 inhibitor, exhibiting high affinity for both GSK-3alpha (Ki = 0.6 nM) and GSK-3beta (Ki = 0.6 nM). It can penetrate the blood-brain barrier (BBB) and accumulate in brain regions, indicating potential use as a PET radiotracer for quantifying GSK-3 in the brain. Target: GSK-3. Smiles: COc1ccc2c(NC(=O)Nc3cccc(n3)C(F)(F)F)ccnc2c1. References: Prabhakaran J, et al. Radiosynthesis and in Vivo Evaluation of [11C]A1070722, a High Affinity GSK-3 PET Tracer in Primate Brain. ACS Chem Neurosci. 2017 Aug 16,8(8):1697-1703.
| Supplier: | TargetMol |
| Supplier-Nr: | T10202 |
Properties
| MW: | 362.31 D |
| Formula: | C17H13F3N4O2 |
Database Information
| CAS : | 1384424-80-9| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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