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BET-IN-8
Item number: TGM-T62275-100mg
Description: BET-IN-8 (Compound 27) is a potent BET inhibitor (Ki: 0.83 µM, Kd: 0.571 µM) that ameliorates LPS-induced sepsis in vivo, showing potential in sepsis treatment. Target: Others
| MW: | 423.48 D |
From 1,440.00€
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Anticancer agent 36
Item number: TGM-T62278-100mg
Description: Anticancer agent 36 (compound 11) is a potent anti-microbial and anti-cancer agent, a sulfonylurea derivative. anticancer agent 36 inhibits the microbial growth of Bacillus mycoides, Escherichia coli and Candida albicans (MIC: 0.156 - 0.039 mg/mL). Anticancer agent 36 inhibited the growth of A549 cells...
| MW: | 423.51 D |
From 1,440.00€
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Antifungal agent 17
Item number: TGM-T62280-100mg
Description: Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 µg/mL). Target: Others
| MW: | 424.13 D |
From 1,440.00€
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AD013
Item number: TGM-T62288-100mg
Description: AD013 is a dual cACE and NEP inhibitor. AD013 is a C-domain selective ACE inhibitor of lenopril-tryptophan synthesis. AD013 has the potential to provide potent anti-hypertensive and cardioprotective effects. Target: Others
| MW: | 424.49 D |
From 1,440.00€
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CDK8-IN-11 hydrochloride
Item number: TGM-T62293-100mg
Description: CDK8-IN-11 hydrochloride is a selective and potent inhibitor of CDK8 (IC50: 46 nM) that inhibits the WNT/beta-catenin signaling pathway and can be utilized for studying colon cancer. Target: Others
| MW: | 424.8 D |
From 1,440.00€
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MEIS-IN-2
Item number: TGM-T62295-100mg
Description: MEIS-IN-2 is an inhibitor of MEIS1. MEIS-IN-2 can be used in studies of cardiac regeneration and haematopoietic stem cell (HSC) regulation. Target: Others
| MW: | 424.88 D |
From 1,440.00€
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HIV-1 inhibitor-44
Item number: TGM-T62319-100mg
Description: HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor with activity against wild-type HIV-1 strains (EC50: 0.209 µM). Target: Others
| MW: | 426.53 D |
From 1,440.00€
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CXCR7 antagonist-1 hydrochloride
Item number: TGM-T62325-25mg
Description: CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of SDF-1 chemokine (also known as CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. Hydrochloride can be used for the prevention of tumor cell proliferation, tumor formation, inflammatory...
| MW: | 426.87 D |
From 1,488.00€
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HDAC2-IN-1
Item number: TGM-T62327-100mg
Description: HDAC2-IN-1 (Compound 17) is an orally active, competitive HDAC2 inhibitor (IC50: 0.5 µM) that crosses the blood-brain barrier and also inhibits HDAC1 (IC50: 1.61 µM) and HDAC8 (IC50: 0.98 µM). Target: Others
| MW: | 426.96 D |
From 1,440.00€
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Autophagy-IN-1
Item number: TGM-T62331-100mg
Description: Autophagy-IN-1 is a potent inhibitor of autophagy/mitophagy that blocks autophagosomal-lysosomal fusion in cancer cells while selectively increasing autophagic flux. It significantly inhibits tumor growth in the HCT116 mouse xenograft tumour model with low toxicity and can be used to study colorectal...
| MW: | 427.45 D |
From 1,440.00€
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Anti-Trypanosoma cruzi agent-1
Item number: TGM-T62333-100mg
Description: Anti-Trypanosoma cruzi agent-1 (Compd E5) demonstrates a potent anti-Toxoplasma effect. Target: Others
| MW: | 427.49 D |
From 1,440.00€
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BChE-IN-3
Item number: TGM-T62336-100mg
Description: BChE-IN-3 is a selective, selective, time-dependent, pseudo-irreversible inhibitor of BChE butyrylcholinesterase (IC50: 56.9 nM).BChE-IN-3 exhibits borderline reversible (time-independent) inhibition of AChE acetylcholinesterase. Target: Others
| MW: | 427.62 D |
From 1,440.00€
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