No results were found for the filter!
Galectin-3 antagonist 2
Item number: TGM-T74538-100mg
Description: Galectin-3, a beta-galactoside-specific carbohydrate recognition protein (lectin), facilitates the migration of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells and demonstrates resistance to pharmaceutical interventions. Target: Galectin
| CAS | 2921603-02-1 |
| MW: | 461.42 D |
From 1,440.00€
*
Anti-inflammatory agent 38
Item number: TGM-T74540-50mg
Description: Anti-inflammatory agent 38 (compound 23d) is a potent Nrf2/HO-1 pathway inhibitor, with an IC 50 value of 0.38 µM for NO . Nrf2/HO-1-IN-1 can significantly reduce the level of ROS in cells. Nrf2/HO-1-IN-1 can be used for researching anti-inflammatory [1] . Target: Others
| MW: | 746.82 D |
Please request pricing for this article.
YM458
Item number: TGM-T74542-100mg
Description: YM458, a potent dual inhibitor of EZH2 and BRD4, exhibits IC50 values of 490 nM and 34 nM, respectively. This compound effectively hinders cell proliferation and colony formation, while also inducing cell cycle arrest and apoptosis in solid tumor cells, making it a viable candidate for anticancer...
| CAS | 2770108-93-3 |
| MW: | 957.62 D |
From 1,440.00€
*
(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine
Item number: TGM-T74544-50mg
Description: (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual-target PROTAC capable of directing ubiquitination and degradation of Smad3 while also elevating HIF-alpha protein levels, exhibiting multipath anti-fibrotic and renal protective functions, making it valuable for renal anemia research [1]....
| CAS | 2347517-69-3 |
| MW: | 750.91 D |
Please request pricing for this article.
FAP-2286 acetate
Item number: TGM-T74547-50mg
Description: FAP-2286 acetate, a conjugate of a fibroblast activation protein (FAP)-binding peptide, exhibits antitumor activity [1]. It can be labeled with radionuclides for diagnostic purposes. Target: Others
| MW: | 1530.83 D |
Please request pricing for this article.
Non-PEGylated/naked ARC1905
Item number: TGM-T74552-50mg
Description: ARC1905, a non-PEGylated/naked anti-C5 RNA aptamer, functions by inhibiting the cleavage of complement factor 5 (C5) into its components, C5a and C5b, without PEG conjugation. This compound is currently being researched for its potential application in the treatment of age-related macular degeneration...
Please request pricing for this article.
YSK 05
Item number: TGM-T74553-2mg
Description: YSK 05, a pH-sensitive cationic lipid, enhances the intracellular trafficking of non-viral vectors, significantly improves gene silencing and hemolytic activities in its modified form YSK 05-MEND, and effectively overcomes the suppression of endosomal escape caused by PEGylation, thereby enhancing siRNA...
| CAS | 1318793-78-0 |
| MW: | 628.07 D |
65.00€
*
alpha1A-AR Degrader 9c
Item number: TGM-T74557-5mg
Description: alpha1A-AR Degrader 9c is a potent, selective, and reversible PROTAC degrader targeting the alpha1A adrenergic receptor (alpha1A-AR) with a DC50 of 2.86 µM. It promotes the proteasomal degradation of the alpha1A-AR and exhibits anti-proliferative effects against PC-3 cells, presenting an IC50 value of...
| CAS | 2863635-02-1 |
| MW: | 829.82 D |
1,279.00€
*
PROTAC_ERRalpha
Item number: TGM-T74559-50mg
Description: PROTAC_ERRalpha is a potent, selective degrader of ERRalpha, efficiently facilitating its proteasomal degradation. This compound specifically targets ERRalpha protein, achieving a degradation efficiency of over 80% [1]. Target: Others
| CAS | 1801547-15-8 |
| MW: | 949.03 D |
Please request pricing for this article.
PROTAC TYK2 degradation agent1
Item number: TGM-T75026-50mg
Description: PROTAC TYK2 Degradation Agent1 is a potent, subtype-selective degrader of TYK2, exhibiting degradation activity with a DC50 of 14 nM. It is utilized in autoimmune disease research [1]. Target: PROTACs
| CAS | 2921556-14-9 |
| MW: | 1056.28 D |
Please request pricing for this article.
G0-C14
Item number: TGM-T75027-100mg
Description: G0-C14, an alkyl-modified polyamidoamine (PAMAM) dendrimer with cationic lipid-like properties, is utilized in the development of macrophage-targeted nanoparticles (NPs) for agent and vaccine delivery [1] [2]. Target: Others
| CAS | 1510653-27-6 |
| MW: | 1790.91 D |
From 100.00€
*
TMV-IN-4
Item number: TGM-T75028-100mg
Description: TMV-IN-4 (Compound 3), a tobacco mosaic virus (TMV) inhibitor, effectively strengthens plant resistance and tolerance to TMV by binding with the TMV helicase. Furthermore, it boosts activities of peroxidase and superoxide dismutase, augmenting tobacco's resilience to TMV infection [1]. Target: Others
| CAS | 1820823-40-2 |
| MW: | 315.36 D |
From 1,298.00€
*