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HDAC1-IN-3
Item number: TGM-T62786-100mg
Description: HDAC1-IN-3 is a potent inhibitor of Pf HDAC1, exhibiting a significant in vivo killing effect on all life cycles of the parasite and displaying antimalarial activity in both wild-type and multidrug-resistant strains of the parasite. Target: Others
| MW: | 453.92 D |
From 1,440.00€
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14alpha-Demethylase/DNA Gyrase-IN-1
Item number: TGM-T62792-100mg
Description: 14alpha-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14alpha-Demethylase/DNA Gyrase, exhibiting antibacterial activity. Target: Others
| MW: | 454.48 D |
From 1,440.00€
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L-690330 hydrate
Item number: TGM-T60820-100mg
Description: L-690330 hydrate is a competitive inositol monophosphatase (IMPase) inhibitor with Ki values for human and bovine frontal cortex IMPase at 0.30 and 0.42 µM, respectively, and Ki values of 0.27 and 0.19 µM for recombinant human and bovine IMPase, respectively [1]. Target: Others
| MW: | 316.14 D |
1,364.00€
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(Z)-Lanoconazole
Item number: TGM-T60853-2mg
Description: (Z)-Lanoconazole is the Z configuration of Lanoconazole, used for investigating dermatophytosis and onychomycosis. It inhibits sterol 14-alpha demethylase, disrupting fungal membrane ergosterol biosynthesis. Lanoconazole is a potent, orally active imidazole antifungal agent with a broad spectrum of...
| MW: | 319.83 D |
47.00€
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NF-kappaB-IN-4
Item number: TGM-T60868-2mg
Description: NF-kappaB-IN-4 (compound 17) is a potent inhibitor of the NF-kappaB pathway that can cross the blood-brain barrier (BBB). It exhibits potential anti-neuroinflammatory activity with low toxicity, making it suitable for researching neuroinflammation-related diseases. NF-kappaB-IN-4 can block IkappaBalpha...
| MW: | 322.34 D |
102.00€
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EB-0150
Item number: TGM-T62793-100mg
Description: EB-0150 is a potent inhibitor of ER alpha-glucosidase (alpha-Glu) I (IC50: 0.73 µM) and (alpha-Glu) II (IC50: 0.0337 µM), and is an N-substituted valerian derivative with broad-spectrum antiviral effects, holding potential for broad-spectrum drug discovery against existing and emerging viruses and for...
| MW: | 454.48 D |
From 1,440.00€
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VEGFR-2-IN-13
Item number: TGM-T62796-100mg
Description: VEGFR-2-IN-13 (Compound 19a) is a potent VEGFR-2 inhibitor (IC50: 3.4 nM) that arrests the HepG2 cell cycle in the G2/M phase and induces apoptosis. Target: Others
| MW: | 454.5 D |
From 1,440.00€
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FLT3/TrKA-IN-1
Item number: TGM-T62801-100mg
Description: FLT3/TrKA-IN-1 is a potent dual kinase inhibitor that targets FLT3 (IC50: 43.8 nM), FLT3-ITD (IC50: 97.2 nM), FLT3-TKD (IC50: 92.5 nM), and TrKA (IC50: 23.6 nM). FLT3/TrKA-IN-1 shows potential for acute myeloid leukaemia (AML) studies. Target: Others
| MW: | 454.56 D |
From 1,440.00€
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Indoluidin E
Item number: TGM-T62802-100mg
Description: Indoluidin E selectively inhibits DHODH and effectively suppresses cancer cell growth. Target: Others
| MW: | 454.56 D |
From 1,440.00€
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STAT3-IN-12
Item number: TGM-T62803-100mg
Description: STAT3-IN-12 is a potent inhibitor of STAT3 signaling, effectively inhibiting IL-6-induced activation of the JAK/STAT3 pathway. It suppresses cancer cell growth and migration, blocks the cell cycle, and induces apoptosis in HCC and oesophageal cancer. Target: Others
| MW: | 454.56 D |
From 745.00€
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SB-612111 hydrochloride
Item number: TGM-T62805-100mg
Description: SB-612111 hydrochloride is a potent, novel orphan receptor for opioid receptors (ORL-1) antagonist with high affinity for hORL-1 and a Ki value of 0.33 nM. SB-612111 hydrochloride is able to act on mu-receptor (Ki: 57.6 nM), kappa SB-612111 hydrochloride effectively antagonized the nociceptive effects...
| MW: | 454.86 D |
From 3,766.00€
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NLRP3-IN-6
Item number: TGM-T62808-100mg
Description: NLRP3-IN-6 (Compound 34) is a selective NLRP3 inflammasome inhibitor. Target: Others
| MW: | 454.97 D |
From 1,440.00€
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