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Cav 2.2/3.2 blocker 1
Item number: TGM-T62586-100mg
Description: Cav 2.2/3.2 blocker 1 (Compound 9e) is a neuronal calcium channel blocker with IC50 values of 1.22 µM for Cav2.2 and 80 µM for Cav3.2, capable of penetrating the central nervous system. Target: Others
| MW: | 442.55 D |
From 1,440.00€
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TCMDC-136230
Item number: TGM-T62588-100mg
Description: TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation. Target: Others
| MW: | 442.62 D |
From 1,440.00€
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AChE-IN-25
Item number: TGM-T62590-100mg
Description: AChE-IN-25 is a selective, potent, non-competitive inhibitor of acetylcholinesterase (AChE) with an IC50 value of 2.95 µM. AChE-IN-25 can be used to study Alzheimer's disease. Target: Others
| MW: | 442.88 D |
From 1,440.00€
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G092
Item number: TGM-T62595-100mg
Description: G092 is a potent inhibitor of the ABC transporter protein MsbA, holding potential for antibacterial drug research. Target: Others
| MW: | 443.32 D |
From 1,440.00€
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Sovesudil hydrochloride
Item number: TGM-T62608-100mg
Description: Sovesudil (PHP-201) hydrochloride is a potent, ATP-competitive Rho kinase (ROCK) inhibitor, acting on ROCK I (IC50: 3.7 nM) and ROCK II (IC50: 2.3 nM), and lowers IOP without causing congestion. Target: Others
| MW: | 443.9 D |
From 1,412.00€
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CD33 splicing modulator 1
Item number: TGM-T62612-25mg
Description: CD33 splicing modulator 1 (Compound 1) is a CD33 splicing modulator that targets the CD33/Siglec 3 myeloid cell surface receptor, known for regulating microglial cell activity, and holds potential for studying neurodegenerative diseases such as Alzheimer's disease. Target: Others
| MW: | 444.5 D |
2,175.00€
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G247
Item number: TGM-T62623-100mg
Description: G247 is a specific inhibitor of MsbA, a wedge of transmembrane structural domains (TMDs) that symmetrically enhances the separation of nucleotide-binding domains (NBDs) and prevents conformational transitions of MsbA. G247 increases the distance between NBDs, thereby inhibiting ATPase activity. Target:...
| MW: | 445.31 D |
From 1,440.00€
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Antibacterial agent 69
Item number: TGM-T62627-100mg
Description: Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 µM). Target: Others
| MW: | 445.49 D |
From 1,440.00€
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HPK1-IN-21
Item number: TGM-T62632-100mg
Description: HPK1-IN-21 is a potent, orally active HPK1 kinase inhibitor with a Ki value of 0.8 nM. Target: Others
| MW: | 445.92 D |
From 1,440.00€
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K027
Item number: TGM-T62634-100mg
Description: K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer's disease. Target: Others
| MW: | 446.14 D |
From 1,440.00€
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MsbA-IN-1
Item number: TGM-T62636-100mg
Description: MsbA-IN-1 is a potent inhibitor of MsbA (IC50: 4 nM). MsbA-IN-1 has anti-E. coli activity (MIC: 79 µM). MsbA-IN-1 fully penetrates the outer membrane of Gram-negative bacteria and exhibits inhibition of MsbA. Target: Others
| MW: | 446.3 D |
From 1,440.00€
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FPR2 agonist 2
Item number: TGM-T62640-100mg
Description: FPR2 agonist 2 is a potent FPR2 agonist with blood-brain barrier permeability that acts on h-FPR2 (EC50: 0.13 nM), inhibiting the production of pro-inflammatory cytokines, counteracting changes in mitochondrial function, and inhibiting caspase-3 activity. Target: Others
| MW: | 446.45 D |
From 747.00€
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