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2-deoxy-D-Glucose
Item number: Cay14325-1
2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis. It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate. 2-deoxy-D-glucose (16 mM) induces apoptosis in...
| Keywords: | Ba 2758, NSC 15193, 2-deoxy-D-arabino-hexose |
| Application: | Non-metabolizable glucose analog |
| CAS | 154-17-6 |
| MW: | 164.2 D |
From 82.00€
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(2S)-Octyl-alpha-hydroxyglutarate
Item number: Cay16367-10
alpha-Hydroxyglutaric acid (2-HG, Cay-16374) is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases. Mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder. Recent studies have found that mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2,...
| Keywords: | (2S)-Octyl-2-HG, 2S-hydroxy-pentanedioic acid, 1-octyl ester |
| CAS | 1391194-64-1 |
| MW: | 260.3 D |
From 85.00€
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L-Ascorbic Acid 2-phosphate (magnesium salt hydrate)
Item number: Cay16457-5
L-Ascorbic acid (vitamin C, Cay-14656) is essential for the synthesis of collagen, with deficiency resulting in scurvy. Notably, humans and other primates, guinea pigs, and certain other animals lack an enzyme necessary for vitamin C synthesis. L-Ascorbic acid 2-phosphate (AA2P) is a long-acting ascorbic acid...
| Keywords: | AA2P, Ascorbyl PM, L-Ascorbic Acid 2-phosphate (magnesium salt), Phospitan C, 2-(dihydrogen phosphate)-L-ascorbic acid,... |
| Application: | Long-acting ascorbic acid derivative, collagen expression stimulator |
| CAS | 1713265-25-8 |
| MW: | 292.6 D |
From 116.00€
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Staurosporine
Item number: Cay81590-1
Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. It inhibits rat recombinant PKC-alpha approximately 100- and 1,000-fold better than PKC-delta and PKC-zeta, respectively. However, Stsp is non-selective in that it also inhibits the activity of a...
| Keywords: | Stsp,... |
| Application: | PKC inhibitor |
| CAS | 62996-74-1 |
| MW: | 466.5 D |
From 55.00€
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D-(+)-Glucose-13C6
Item number: Cay26707-1
D-(+)-Glucose-13C6 is intended for use as an internal standard for the quantification of D-(+)-glucose (Cay-23733) by GC- or LC-MS. D-(+)-Glucose is a monosaccharide that occurs in nature and is used by organisms as an energy source. D-(+)-Glucose is the more common enantiomer of L-(-)-glucose (Cay-20829).Formal...
| Keywords: | D-glucose-1,2,3,4,5,6-13C6 |
| Application: | GC-MS, LC-MS, internal standard, quantification |
| CAS | 110187-42-3 |
| MW: | 186.1 D |
From 85.00€
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Urea, ultra pure
Item number: 50250.1
Purity: >=99.5%. Suitable for electrophoresis
| Application: | Denaturing agent |
| CAS | 57-13-6 |
| MW: | 60.06 |
46.00€
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Ferrostatin-1
Item number: Cay17729-5
Ferrostatin-1 is a ferroptosis inhibitor. It inhibits cell death induced by the ferroptosis inducers erastin (Cay-17754, EC50 = 60 nM) and RSL3, but not by hydrogen peroxide, rotenone, or staurosporine, in HT-1080 cells when used at a concentration of 0.5 µM. Ferrostatin-1 (0.5 µM) inhibits erastin-induced...
| Keywords: | Fer-1, 3-amino-4-(cyclohexylamino)-benzoic acid, ethyl ester |
| Application: | Ferroptosis inhibitor |
| CAS | 347174-05-4 |
| MW: | 262.4 D |
From 85.00€
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(+)-JQ1
Item number: Cay11187-5
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces...
| Keywords: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid,... |
| Application: | BRD4 inhibitor |
| CAS | 1268524-70-4 |
| MW: | 457 D |
From 44.00€
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Nigericin, sodium salt
Item number: AG-CN2-0020-M005
Isolated from Streptomyces hygroscopicus. Antibiotic. High affinity ionophore for monovalent cations such as H, K, Na, Pb2. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity. Disrupts membrane potential and Golgi apparatus in mitochondria. NLRP3/NALP3 activator. Signals through...
| Keywords: | Antibiotic K 178, Helexin C, Polyetherin A, BRN 1696755, Azalomycin M, Antibiotic X-464 |
| Application: | Ionophore |
| CAS | 28643-80-3 |
From 72.00€
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NEW
Crotamiton
Item number: Cay23943-5
N-Ethyl-o-Crotonotoluidide, N-ethyl-N-(2-methylphenyl)-2-butenamide
| Keywords: | N-Ethyl-o-Crotonotoluidide, N-ethyl-N-(2-methylphenyl)-2-butenamide |
| Application: | Antipruritic |
| CAS | 483-63-6 |
| MW: | 203.3 D |
From 314.00€
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Carmustine
Item number: LKT-C0173.100
Carmustine is an antitumor agent.
| Keywords: | BCNU, bis-chloroethylnitrosourea |
| Application: | Anticancer agent |
| CAS | 154-93-8 |
| MW: | 214,05 D |
From 104.00€
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NADP+, disodium salt
Item number: 62263.1
Assay: >85% enzymatically
| Keywords: | beta-Nicotinamide-adenine-dinucleotide phosphate Na2-salt |
| CAS | 24292-60-2 |
| MW: | 787.40 D |
From 259.00€
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