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PI3K-IN-46
Item number: TGM-T64392-100mg
Description: PI3K-IN-46 is a specific inhibitor of PI3Kgamma. Target: PI3K. Smiles: C(C1=CC2=C(C=C1)N=CC=C2)=C3C(=O)N=C(N)S3. References: Chen S, et al. Synthesis and activity of quinolinyl-methylene-thiazolinones as potent and selective cyclin-dependent kinase 1 inhibitors. Bioorg Med Chem Lett. 2007 Apr...
| CAS | 304645-61-2 |
| MW: | 255.3 D |
From 93.00€
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6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,...
Item number: TGM-T64393-100mg
Description: 6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile is a biologically active compound, which is utilized for research in the fields of chemistry and life sciences. Target: Others. Smiles:...
| CAS | 1314134-92-3 |
| MW: | 417.54 D |
From 46.00€
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GW 833972A
Item number: TGM-T64394-10mg
Description: GW 833972A is a selective CB2 receptor agonist that inhibits induced neural depolarization and citric acid-induced cough in an animal model. Target: Cannabinoid Receptor. Smiles: Cl.FC(F)(F)c1nc(Nc2cccc(Cl)c2)ncc1C(=O)NCc1ccncc1. References: Belvisi MG, et al. Inhibitory activity of the novel CB2...
| CAS | 1092502-33-4 |
| MW: | 727.93 D |
From 168.00€
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Antiviral agent 38
Item number: TGM-T64396-10mg
Description: 2H-Pyrido[2',1':3,4]pyrazino[1,2-b]indazole-3-carboxylic acid, 6-(1, 1-Dimethylethyl)-6, 7-Dihydro-10 -(3-methoxypropoxy)-2-oxo-, (6R)- has antibacterial and antiviral activity and can be used to study Hepatitis B virus. Target: Antiviral. Smiles:...
| CAS | 2247932-38-1 |
| MW: | 425.48 D |
From 77.00€
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(e)-3-(3,4-dihydroxyphenyl)-n-(2-(3,4-dihydroxyphenyl)eth...
Item number: TGM-T64398-100mg
Description: (e)-3-(3,4-dihydroxyphenyl)-n-(2-(3,4-dihydroxyphenyl)ethyl)-2-propenamide is capable of interacting with proteins and other molecules in a variety of ways and has been used to study protein-protein interactions as well as enzyme-substrate interactions. Target: Others. Smiles:...
| MW: | 315.32 D |
From 1,440.00€
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CGP 57380
Item number: TGM-T6440-100mg
Description: CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 µM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. Target: Apoptosis, MNK. Smiles: Nc1ncnc2[nH]nc(Nc3ccc(F)cc3)c12. References: Knauf U, et al. Mol Cell Biol. 2001, (16), 5500-5511.
| Keywords: | MNK1 Inhibitor |
| Application: | MAPK-interacting kinase 1 inhibitor |
| CAS | 522629-08-9 |
| MW: | 244.23 D |
From 34.00€
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Gadodiamide Hydrate
Item number: TGM-T6508-1mL
Description: Gadodiamide Hydrate (Omniscan), a nonionic Gd3+ chelate, is frequently injected i.v. into magnetic resonance imaging (MRI) to enhance contrast. Target: Others. Smiles: O.[Gd+3].CNC(=O)CN(CCN(CCN(CC([O-])=O)CC(=O)NC)CC([O-])=O)CC([O-])=O. References: Harpur ES, et al. Invest Radiol, 1993, 28, S28-43.
| Keywords: | Omniscan |
| Application: | Diagnostic aid (contrast medium) |
| CAS | 122795-43-1 |
| MW: | 591.67 D |
From 30.00€
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G-418 disulfate
Item number: TGM-T6512-1g
Description: G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic that selectively inhibits eukaryotic protein synthesis by blocking peptide chain elongation. Target: Antibacterial, Antibiotic. Smiles:...
| Keywords: | Geneticin, Antibiotic G-418 sulfate, G418 Sulfate, Geneticin sulfate |
| Application: | Apoptosis inducer |
| CAS | 108321-42-2 |
| MW: | 692.71 D |
From 40.00€
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Bisindolylmaleimide I
Item number: TGM-T6513-100mg
Description: Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor, exhibiting a Ki of 14 nM. Target: PDGFR, PKC. Smiles: CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc12. References: Toullec D, et al. J Biol Chem. 1991, 266(24), 15771-15781.
| Keywords: | Go 6850, GF109203X |
| Application: | PKC inhibitor |
| CAS | 133052-90-1 |
| MW: | 412.48 D |
From 57.00€
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3-Hydroxybutyric acid sodium
Item number: TGM-T65133-10g
Description: 3-Hydroxybutyric acid sodium (beta-Hydroxybutyric acid sodium) is a metabolite found in type I diabetic patients that regulates membrane lipids. Target: Endogenous Metabolite. Smiles: [Na+].C[C@@H](O)CC([O-])=O. References: Hsu TT, et al. 3-Hydroxybutyric acid interacts with lipid monolayers at...
| Keywords: | beta-Hydroxybutyric acid sodium |
| MW: | 126.09 D |
From 29.00€
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Glasdegib
Item number: TGM-T6514-100mg
Description: Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2. Target: Smo, Hedgehog/Smoothened. Smiles: CN1CC[C@H](C[C@@H]1c1nc2ccccc2[nH]1)NC(=O)Nc1ccc(cc1)C#N. References: Munchhof MJ, et al. ACS Med Chem Lett. 2011, 3(2), 106-111.
| Keywords: | PF-04449913 |
| Application: | Targets smoothened (SMO) |
| CAS | 1095173-27-5 |
| MW: | 374.44 D |
From 35.00€
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Go6976
Item number: TGM-T6515-100mg
Description: Go6976 is a small molecule inhibitor of protein kinase C (PKC). Go6976 has been widely used in biomedical research as a tool to study the role of PKC in various physiological and pathophysiological processes. Target: PKC. Smiles: Cn1c2ccccc2c2c3C(=O)NCc3c3c4ccccc4n(CCC#N)c3c12. References: Hayamitsu...
| Keywords: | Gö 6976 |
| Application: | PKCalpha / PKCbeta1 inhibitor |
| CAS | 136194-77-9 |
| MW: | 378.43 D |
From 65.00€
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