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AcLysValCit-PABC-DMAE-SW-163D
Item number: TGM-T18737-100mg
Description: AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugate for antibody-drug conjugates (ADCs), incorporating the natural bis-intercalator SW-163D through an AcLysValCit-PABC-DMAE linker[1]. Target: Others, Drug-Linker Conjugates for ADC. Smiles:...
| CAS | 2411007-69-5 |
| MW: | 1817.07 D |
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t-Boc-Aminooxy-PEG12-acid
Item number: TGM-T18738-100mg
Description: t-Boc-Aminooxy-PEG12-acid is a polyethylene glycol (PEG)-based PROTAC linker used for synthesizing PROTACs [1]. Target: Others. Smiles: O=C(OC(C)(C)C)NOCCOCCOCC OCCOCCOCCO CCOCCOCCOC COCCOCCOCC C(O)=O. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the...
| MW: | 733.84 D |
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t-Boc-Aminooxy-PEG12-Boc
Item number: TGM-T18739-100mg
Description: t-Boc-Aminooxy-PEG12-Boc is a PEG-derived PROTAC linker used in the synthesis of PROTACs[1]. Target: Others. Smiles: O=C(OC(C)(C)C)NOCCOCCOCC OCCOCCOCCO CCOCCOCCOC COCCOCCOCC C(OC(C)(C)C)=O. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of...
| MW: | 789.95 D |
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PPQ-102
Item number: TGM-T1874-100mg
Description: PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM). Target: Autophagy, CFTR. Smiles: Cc1ccc(o1)C1Nc2ccccc2-n2c1c1n(C)c(=O)n(C)c(=O)c1c2-c1ccccc1. References: Tradtrantip L, et al. J Med Chem. 2009 Oct 22,52(20):6447-55.
| Keywords: | PPQ 102, PPQ102, CFTR Inhibitor |
| Application: | CFTR inhibitor |
| CAS | 931706-15-9 |
| MW: | 438.48 D |
From 33.00€
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t-Boc-Aminooxy-PEG12-NHS ester
Item number: TGM-T18740-100mg
Description: t-Boc-Aminooxy-PEG12-NHS ester, a polyethylene glycol (PEG) derived PROTAC linker, is specifically designed for the synthesis of PROTACs [1]. Target: Others. Smiles: O=C(OC(C)(C)C)NOCCOCCOCC OCCOCCOCCO CCOCCOCCOC COCCOCCOCC C(ON1C(CCC1=O)=O)=O. References: An S, et al. Small-molecule PROTACs: An...
| MW: | 830.91 D |
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t-Boc-Aminooxy-PEG4-NHS ester
Item number: TGM-T18741-10mg
Description: t-Boc-Aminooxy-PEG4-NHS ester is a polyethylene glycol (PEG) derivative that functions as a linker for PROTAC synthesis [1]. Target: Others. Smiles: O=C(OC(C)(C)C)NOCCOCCOCC OCCOCCC(=O)ON1C(=O)CCC1=O. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development...
| CAS | 2401831-99-8 |
| MW: | 478.49 D |
From 56.00€
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t-Boc-Aminooxy-PEG5-azide
Item number: TGM-T18742-100mg
Description: t-Boc-Aminooxy-PEG5-azide is a polyethylene glycol (PEG) derivative functioning as a linker for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. Target: Others. Smiles: [N-]=[N+]=NCCOCCOCCO CCOCCOCCON C(=O)OC(C)(C)C. References: An S, et al. Small-molecule PROTACs: An emerging and promising...
| CAS | 2250216-95-4 |
| MW: | 422.47 D |
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t-Boc-Aminooxy-PEG7-amine
Item number: TGM-T18743-100mg
Description: t-Boc-Aminooxy-PEG7-amine, a polyethylene glycol (PEG) derivative, serves as a PROTAC linker for synthesizing PROTACs [1]. Target: Others. Smiles: O=C(OC(C)(C)C)NOCCOCCOCC OCCOCCOCCO CCOCCN. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of...
| CAS | 2226611-29-4 |
| MW: | 484.58 D |
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t-Boc-Aminooxy-PEG7-bromide
Item number: TGM-T18744-100mg
Description: t-Boc-Aminooxy-PEG7-bromide is a polyethylene glycol (PEG)-based bifunctional linker used in synthesizing proteolysis targeting chimeras (PROTACs)[1]. Target: Others. Smiles: O=C(OC(C)(C)C)NOCCOCCOCC OCCOCCOCCO CCOCCBr. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach...
| CAS | 2353410-15-6 |
| MW: | 548.46 D |
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t-Boc-Aminooxy-PEG8-alcohol
Item number: TGM-T18745-100mg
Description: t-Boc-Aminooxy-PEG8-alcohol is a PEGylated PROTAC linker appropriate for synthesizing PROTACs [1]. Target: Others. Smiles: O=C(OC(C)(C)C)NOCCOCCOCC OCCOCCOCCO CCOCCO. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs....
| CAS | 2353410-14-5 |
| MW: | 485.57 D |
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t-Boc-Aminooxy-PEG8-Ms
Item number: TGM-T18746-100mg
Description: t-Boc-Aminooxy-PEG8-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles: O=C(NOCCOCCOCC OCCOCCOCCO...
| MW: | 563.66 D |
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TAMRA-PEG3-biotin
Item number: TGM-T18747-100mg
Description: TAMRA-PEG3-biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles:...
| CAS | 2279944-59-9 |
| MW: | 830.99 D |
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