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Staurosporine
Item number: LKT-S7600.1
A protein kinase C inhibitor which induces apoptosis in many cell types. Experimental results obtained in a cell -free assay suggest that cytoplasmic proteins directly modulated by staurosporine may be involved in signaling the induction of DNA fragmentation and apoptosis.
| Keywords: | AM-2282, STS |
| Application: | PKC inhibitor |
| CAS | 62996-74-1 |
| MW: | 466,5 D |
From 64.00€
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Spermine NONOate
Item number: Cay82150-10
Spermine NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 39 minutes and 230 minutes at 37°C and 22-25°C, respectively, (pH 7.4) to liberate 2 moles of NO per mole of parent compound.Formal Name:...
| Keywords: | (Z)-1-[N-[3-aminopropyl]-N-[4-(3-aminopropylammonio)butyl]-amino]diazen-1-ium-1,2-diolate |
| Application: | NO donor |
| CAS | 136587-13-8 |
| MW: | 262.4 D |
From 72.00€
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(±)-Nutlin-3
Item number: Cay10004372-5
(±)-Nutlin-3 is a racemic mixture of the p53-Mdm2 protein-protein interaction inhibitor (-)-nutlin-3 (Cay-18585) and its less active enantiomer (+)-nutlin-3 (Cay-10009816). In vivo, (±)-nutlin-3 (200 mg/kg twice daily) reduces tumor volume in an SJSA-1 osteosarcoma mouse xenograft model.Formal Name:...
| Keywords: | rel-4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-pi... |
| Application: | Cell cycle arrest promotor |
| CAS | 548472-68-0 |
| MW: | 581.5 D |
From 57.00€
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ADHP
Item number: Cay10010469-10
ADHP is a highly sensitive, stable substrate for horseradish peroxidase (HRP) that enables selective detection of H2O2. This colorless, non-fluorescent reagent reacts with H2O2 to produce the fluorescent compound resorufin, which can be analyzed using an excitation wavelength of 520-550 nm and an emission wavelength...
| Keywords: | A 6550, ADHP, Amplex Red(R), 1-(3,7-dihydroxy-10H-phenoxazin-10-yl)-ethanone |
| Application: | HRP substrate |
| CAS | 119171-73-2 |
| MW: | 257.2 D |
From 38.00€
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(1S,3R)-RSL3
Item number: Cay19288-5
(1S,3R)-RSL3 is a ferroptosis inducer and is canonically known as an inhibitor of glutathione peroxidase 4 (GPX4). It inhibits GPX4 in a context-dependent manner: (1S,3R)-RSL3 inhibits GPX4 in the presence of cell cytosol or recombinant human 14-3-3epsilon, an adaptor protein, but does not inhibit recombinant human...
| Keywords: | (1S,3R)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylic acid,... |
| Application: | GPX4 inhibitor |
| CAS | 1219810-16-8 |
| MW: | 440.9 D |
From 53.00€
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Biotinyl tyramide
Item number: CDX-B0270-M100
White to light pink solid. Soluble in acetonitrile. Biotin derivative. Substrate of the horseradish peroxidase enzyme and used as a reagent to amplify immunohistochemical signals. It is based on the HRP-catalyzed deposition of tyramide conjugates (such as biotinyl-tyramide) on a solid phase. Subsequent reaction with...
| Keywords: | Biotin-Phenol, BP, N-(4-Hydroxyphenethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide |
| Application: | Biotin derivative, HRP substrate, IHC signal amplifier |
| CAS | 41994-02-9 |
| MW: | 363,5 D |
From 199.00€
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Beauvericin
Item number: Cay11426-1
Beauvericin is a mycotoxin originally derived from B. bassiana, a common fungal parasite of arthropods. It is also produced by the fungus Fusarium, a pathogen of insects and plants. Beauvericin is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 µM. In...
| Keywords: | cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)... |
| Application: | Mycotoxin, Apoptosis inducer |
| CAS | 26048-05-5 |
| MW: | 784 D |
From 53.00€
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Calbryte(TM)-590 AM
Item number: ABD-20702
Ex: 573 nm. Em: 588 nm. Soluble in: DMSO. The intracellular calcium flux assay is a widely used method in monitoring signal transduction pathways and high throughput screening of G protein-coupled receptors (GPCRs) and calcium channel targets. Followed by Rhod-2 being introduced in 1989, Rhod-4 and Cal-590 were...
| Application: | FC |
| MW: | 1218,77 D |
From 291.00€
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MAHMA NONOate
Item number: Cay82130-10
MAHMA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 1 minute and 3 minutes at 37°C and 22-25°C, respectively, (pH 7.4) to liberate 2 moles of NO per mole of parent compound.Formal Name:...
| Keywords: | Methylamine hexamethylene methylamine NONOate, (Z)-1-[N-Methyl-N-[6-(N-methylammoniohexyl)amino]]diazen-1-ium-1,2-diolate |
| Application: | NO donor |
| CAS | 146724-86-9 |
| MW: | 204.3 D |
From 57.00€
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Doxycycline Hyclate
Item number: LKT-D5897.25
An antimicrobial agent. Used in the treatment of severe purulent inflammatory diseases such as pneumonia, lung abscesses, pyothorax, skin and soft tissue infections, peritonitis, purulent cholangitis and others
| Application: | Antimicrobial agent |
| CAS | 24390-14-5 |
| MW: | 512,9 D |
From 57.00€
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DEA NONOate
Item number: Cay82100-10
DEA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2 minutes and 16 minutes at 37°C and 22-25°C, pH 7.4, respectively, to liberate 1.5 moles of NO per mole of parent compound.Formal Name: Diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate....
| Keywords: | DEA/NO, Diethylamine NONOate, Diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate |
| Application: | NO donor |
| CAS | 372965-00-9 |
| MW: | 206.3 D |
From 53.00€
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SB 202190
Item number: Cay10010399-10
SB 202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a range of other kinases, including other MAP kinases (ERKs,...
| Keywords: | 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-phenol |
| Application: | MAP kinases Inhibitor |
| CAS | 152121-30-7 |
| MW: | 331.3 D |
From 75.00€
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