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Phepropeptin A
Item number: Cay10008108-1
A cyclic peptide with proteasome inhibitory activity, inhibits isolated mouse liver proteasomes (IC50 = 21 µg/ml). Formulation: A powder. InChI:...
| Keywords: | Cyclic(Leu-D-Leu-Val-Leu-D-Phe-Pro),... |
| Application: | Cyclic peptide, proteasome inhibitory agent |
| CAS | 396729-23-0 |
| MW: | 682.9 D |
961.00€
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Phepropeptin B
Item number: Cay10008109-1
A cyclic peptide with proteasome inhibitory activity, inhibits isolated mouse liver proteasomes (IC50 = 11 µg/ml). Formulation: A powder. InChI:...
| Keywords: | Cyclic(Leu-D-Phe-Pro-Phe-D-Leu-Val), cyclo(L-leucyl-D-phenylalanyl-L-prolyl-L-phenylalanyl-D-leucyl-L-valyl) |
| Application: | Cyclic peptide, proteasome inhibitory agent |
| CAS | 396729-24-1 |
| MW: | 716.9 D |
961.00€
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Phepropeptin D
Item number: Cay10008111-1
A cyclic peptide with proteasome inhibitory activity, inhibits isolated mouse liver proteasomes (IC50 = 7.8 µg/ml). Formulation: A powder. InChI:...
| Keywords: | Cyclic(Leu-D-Phe-D-Pro-Phe-D-Leu-xi-Ile),... |
| Application: | Cyclic peptide, proteasome inhibitory agent |
| CAS | 396729-26-3 |
| MW: | 730.94 D |
961.00€
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BAY 60-2770
Item number: Cay20077-1
An activator of soluble guanylate cyclase (EC50s = 592 and 573 nM for the alpha1beta1 and alpha2beta1 isoforms, respectively), increases cGMP levels in, and inhibits the aggregation of, collagen- or thrombin-activated washed isolated human platelets, effects that can be potentiated by ODQ, inhibits...
| Keywords: | 4-[[(4-carboxybutyl)[2-[5-fluoro-2-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methoxy]phenyl]ethyl]amino]methyl]-benzoic acid |
| Application: | Soluble guanylate cyclase activator |
| CAS | 1027642-43-8 |
| MW: | 623.6 D |
From 70.00€
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Apararenone
Item number: Cay30671-10
A non-steroidal mineralocorticoid receptor antagonist (Ki = 0.104 µM for the human receptor), selective for mineralocorticoid receptors over ERalpha and ERbeta and glucocorticoid, progesterone, and androgen receptors (IC50s = >100 µM for all), increases the urinary ratio of sodium to potassium in adrenalectomized...
| Keywords: | MT-3995, N-[4-(4-fluorophenyl)-3,4-dihydro-2,2-dimethyl-3-oxo-2H-1,4-benzoxazin-7-yl]-methanesulfonamide |
| Application: | Non-steroidal mineralocorticoid receptor antagonist |
| CAS | 945966-46-1 |
| MW: | 364.4 D |
From 90.00€
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Taminadenant
Item number: Cay32799-10
An adenosine A2A receptor antagonist (Ki = 12 nM), selective for adenosine A2A receptors over adenosine A1-, A2B-, and A3 receptors (Kis = 2,500, 1,000, and 5,000 nM, respectively), increases the levels of IFN-gamma secreted by tumor-associated T cells isolated from patient-derived lung tumors at 1 µM when used in...
| Keywords: | NIR 178, PBF-509, 5-bromo-2,6-di-1H-pyrazol-1-yl-4-pyrimidinamine |
| Application: | Adenosine A2A receptor antagonist |
| CAS | 1337962-47-6 |
| MW: | 306.1 D |
From 60.00€
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Trifluralin
Item number: Cay35476-100
A dinitroaniline herbicide, inhibits photosynthetic electron transport, ATP synthesis, and cytochrome f reduction in isolated spinach chloroplasts, decreases cotton (G. hirsutum) plant height when applied to the soil prior to planting at 1.68 kg/ha, induces ROS production in V79 fibroblasts and genotoxicity in...
| Keywords: | 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)-benzenamine |
| Application: | Dinitroaniline herbicide |
| CAS | 1582-09-8 |
| MW: | 335.3 D |
From 208.00€
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5-Hexynoic Acid
Item number: Cay35507-1
A protein labeling compound, has been used to label proteins at acylation sites in a fatty acid synthase-dependent manner, can be further conjugated to fluorescent probes or biotin via click chemistry for protein identification. Formulation: A neat liquid. InChI: InChI=1S/C6H8O2/c1-2-3-4-5-6(7)8/h1H,3-5H2,(H,7,8)....
| Keywords: | 5-Hexynoate, ALK-4 |
| Application: | Protein labeling compound, click chemistry |
| CAS | 53293-00-8 |
| MW: | 112.1 D |
From 40.00€
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NPD4928
Item number: Cay36598-1
An FSP1 inhibitor and ferroptosis enhancer, binds to FSP1 and inhibits its activity in a cell-free NADH consumption assay, synergistically enhances RSL3-induced cytotoxicity in PANC-1 prostate cancer cells at 3 µM, induces cytotoxicity in PC3, MKN74, DU145, MIA PaCa-2, and A549 cells (IC50s = 95-155 nM,...
| Keywords: | 2-[(9,10-dihydro-3,4,8,8-tetramethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-5-yl)oxy]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]... |
| Application: | FSP1 inhibitor, ferroptosis enhancer |
| CAS | 956965-61-0 |
| MW: | 504.57 D |
From 76.00€
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Poseltinib
Item number: Cay37324-1
An irreversible inhibitor of BTK (IC50 = 1.95 nM), selective for BTK over a panel of 85 additional kinases at 2 µM but does inhibit BMX, Tec, and TXK (IC50s = 0.64, 4.57, and 4.62 nM, respectively), as well as EGFR, Blk, and JAK3 (IC50s = 4.96, 13.5, and 14.6 nM, respectively), decreases the levels of CD40, CD69, or...
| Keywords: | HM71224, LY3337641, N-[3-[[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]furo[3,2-d]pyrimidin-4-yl]oxy]phenyl]-2-propenamide |
| Application: | Irreversible BTK inhibitor |
| CAS | 1353552-97-2 |
| MW: | 470.5 D |
From 40.00€
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Atractylon
Item number: Cay37568-10
A sesquiterpene with diverse biological activities, scavenges DPPH radicals in a cell-free assay at 0.01, 0.1, or 1 mg/ml, antagonist of dopamine D2 receptors (IC50 = 2.5 µM), inhibitor of 5-LO, (IC50 = 25.1 µM), inhibits tert-butyl hydroperoxide-induced release of ALT and LDH and increases in intracellular MDA and...
| Keywords: | 4,4aS,5,6,7,8,8aR,9-octahydro-3,8a-dimethyl-5-methylene-naphtho[2,3-b]furan |
| Application: | Bioactive sesquiterpene |
| CAS | 6989-21-5 |
| MW: | 216.3 D |
From 60.00€
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Nonafluoro-3,6-dioxaheptanoic Acid
Item number: Cay37917-100
A perfluoroalkyl ether carboxylic acid, has been found as an environmental contaminant in watersheds. Formulation: A liquid. InChI: InChI=1S/C5HF9O4/c6-2(7,1(15)16)17-3(8,9)4(10,11)18-5(12,13)14/h(H,15,16). InChIKey: PPWRLPJIHGWGFH-UHFFFAOYSA-N. SMILES: O=C(C(F)(OC(F)(C(F)(OC(F)(F)F)F)F)F)O
| Keywords: | NFDHA, Perfluoro-3,6-dioxaheptanoic Acid, PFO2HpA, 2,2-difluoro-2-[1,1,2,2-tetrafluoro-2-(trifluoromethoxy)ethoxy]-acetic... |
| Application: | Perfluoroalkyl ether carboxylic acid (PFECA) |
| CAS | 151772-58-6 |
| MW: | 296 D |
From 91.00€
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