7-Azido-4-methylcoumarin

7-Azido-4-methylcoumarin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-CR1-3525-M001 1 mg -

3 - 9 business days*

44.00€
AG-CR1-3525-M005 5 mg -

3 - 9 business days*

88.00€
 
Soluble in DMSO. Highly sensitive and selective fluorogenic H2S probe [1-3]. The aromatic azide... more
Product information "7-Azido-4-methylcoumarin"
Soluble in DMSO. Highly sensitive and selective fluorogenic H2S probe [1-3]. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with ?ex = 365 nm and ?em = 450 nm. Photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). Probe to monitor the enzymatic production of H2S in vitro and to visualize H2S in living cells. Tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine ?-lyase (CGL) and tryptophan synthase (TS)). Tool to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. Suitable for high-throughput screening. Caution: Use of this product with DTT, TCEP and/or biological thiols at concentrations of >25 mM should be avoided for maximum efficiency.
Keywords: AzMC
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-CR1-3525

Properties

Application: Fluorogenic H2S probe
MW: 201,2 D
Formula: C10H7N3O2
Purity: >98%
Format: Solid

Database Information

CAS : 95633-27-5| Matching products
KEGG ID : K01697 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H319, H335
P Phrases: P261, P271, P280, P312
Caution
Our products are for laboratory research use only: Not for administration to humans!
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