6-Chloropurine riboside-5'-triphosphate (sodium salt)

6-Chloropurine riboside-5'-triphosphate is an inhibitor of the RNA triphosphatase mRNA-capping enzyme subunit beta (Cet1, IC50 = 2 µM for the GTPase activity of the S. cerevisiae enzyme) and a phosphorylated form of 6-chloropurine riboside (Cay-36002). It also activates E. coli aspartate carbamoyltransferase (EC50 = 0.76 mM). 6-Chloropurine riboside-5'-triphosphate has been used in the synthesis of cytokinins with anticancer activity and a photoclickable form of ATP.Formal Name: 6-chloro-9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-beta-D-ribofuranosyl]-9H-purine, tetrasodium salt. Synonyms: 6-chloro PuTP. Molecular Formula: C10H10ClN4O13P3 . 4Na. Formula Weight: 614.5. Purity: >95%. Formulation: (Request formulation change), A solution in water. Solubility: Water: Soluble. SMILES: O[C@@H]1[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@@H](N2C3=NC=NC(Cl)=C3N=C2)[C@@H]1O.[Na+].[Na+].[Na+].[Na+]. InChi Code: InChI=1S/C10H14ClN4O13P3.4Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20,,,,/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,18,19,20),,,,/q,4*+1/p-4/t4-,6-,7-,10-,,,,/m1..../s1. InChi Key: UYZNRZQPHVRPII-KWIZKVQNSA-J.