5Z-7-Oxozeaenol
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-T14055-1mg | 1 mg |
5 - 10 business days* |
307.00€
|
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| TGM-T14055-5mg | 5 mg |
5 - 10 business days* |
693.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: 5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of... more
Product information "5Z-7-Oxozeaenol"
Description: 5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-beta-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM. Target: MAPK, MEK, FLT, PDGFR, Src, Antibiotic, VEGFR. Smiles: COc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O. References: Dakas PY, et al. Modular synthesis of radicicol A and related resorcylic acid lactones, potent kinase inhibitors. Angew Chem Int Ed Engl. 2007,46(36):6899-902.
| Keywords: | FR148083, L783279, LL-Z 1640-2 |
| Supplier: | TargetMol |
| Supplier-Nr: | T14055 |
Properties
| Application: | TAK1 inhibitor |
| MW: | 362.37 D |
| Formula: | C19H22O7 |
Database Information
| CAS : | 253863-19-3| Matching products |
| KEGG ID : | K04427 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301 |
| P Phrases: | P264, P270, P301+310, P321, P330, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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