(5E)-7-Oxozeaenol

(5E)-7-Oxozeaenol
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay29840-1 1 mg -

6 - 10 business days*

235.00€
Cay29840-5 5 mg -

6 - 10 business days*

874.00€
 
(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and... more
Product information "(5E)-7-Oxozeaenol"
(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities. It inhibits TGF-beta-activated kinase 1 (TAK-1, IC50 = 1.3 µM). (5E)-7-Oxozeaenol inhibits proliferation of MCF-7, H460, SF-268, HT-29, and MDA-MB-435 human cancer cells with IC50 values of 4.9, 1.2, 5.6, 4.4, and 5.5 µM, respectively.Formal Name: (3S,5E,8S,9S,11E)-3,4,9,10-tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione. CAS Number: 1198574-97-8. Synonyms: LL-Z 1640-2. Molecular Formula: C19H22O7. Formula Weight: 362.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: soluble, DMSO: soluble, Ethanol: soluble, Methanol: soluble. SMILES: COC1=CC(O)=C(C(O[C@@H](C)C/C=C/C([C@@H](O)[C@@H](O)C/C=C/2)=O)=O)C2=C1. InChi Code: InChI=1S/C19H22O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h3-4,6-7,9-11,15,18,21-23H,5,8H2,1-2H3/b6-4+,7-3+/t11-,15-,18+/m0/s1. InChi Key: NEQZWEXWOFPKOT-ULSULSEOSA-N. Origin: Fungus/Curvularia sp..
Keywords: LL-Z 1640-2, (3S,5E,8S,9S,11E)-3,4,9,10-tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione
Supplier: Cayman Chemical
Supplier-Nr: 29840

Properties

Application: Resorcylic acid lactone, anticancer agent
MW: 362.4 D
Formula: C19H22O7
Purity: >95%
Format: Solid

Database Information

CAS : 1198574-97-8| Matching products
KEGG ID : K04427 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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