5beta-Cholestane-3alpha,7alpha,12alpha,25-tetrol

5beta-Cholestane-3alpha,7alpha,12alpha,25-tetrol is a bile acid alcohol. It induces activation of G protein-coupled bile acid receptor 1 (GPBAR1), also known as TGR5, in HEK293 cells expressing the human receptor when used at concentrations ranging from 0. to 10 µM. Blood, fecal, and bile levels of 5beta-cholestane-3alpha,7alpha,12alpha,25-tetrol are increased in patients with cerebrotendinous xanthomatosis (CTX), a progressive metabolic leukodystrophy.. Solulibility: DMSO: Soluble: = 10 mg/ml: Ethanol: Soluble: = 10 mg/ml.