5beta,6beta-epoxy Cholestanol

5beta,6beta-epoxy Cholestanol is an oxidative metabolite of cholesterol that is formed via radical and non-radical oxidation of cholesterol at the 5,6-double bond. It induces release of lactate dehydrogenase (LDH) and apoptosis in macrophage-differentiated U937 cells. 5beta,6beta-epoxy Cholestanol has been found in human fatty streaks and advanced atherosclerotic lesions but is not present in normal aortic tissue.Formal Name: 5beta,6beta-epoxy-cholestan-3beta-ol. CAS Number: 4025-59-6. Synonyms: Cholesterol beta-Epoxide, 5beta,6beta-Epoxycholesterol, 5beta,6beta-Epoxycholestan-3beta-ol, NSC 148940. Molecular Formula: C27H46O2. Formula Weight: 402.7. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 0.1 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml. SMILES: C[C@H](CCCC(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])C[C@@H]4[C@]5(O4)C[C@@H](O)CC[C@]5(C)[C@@]3([H])CC[C@@]21C. InChi Code: InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24-27(29-24)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24-,25-,26-,27-/m1/s1. InChi Key: PRYIJAGAEJZDBO-DTLXENBRSA-N.