5-Fluorocytosine

5-Fluorocytosine
Item number Size Datasheet Manual SDS Delivery time Quantity Price
CDX-F0077-G001 1 g - -

3 - 9 business days*

183.00€
CDX-F0077-G005 5 g - -

3 - 9 business days*

734.00€
 
White to off-white powder. Soluble in water. Fluorinated pyrimidine analog. Antimycotic prodrug... more
Product information "5-Fluorocytosine"
White to off-white powder. Soluble in water. Fluorinated pyrimidine analog. Antimycotic prodrug that is converted by cytosine deaminase to 5-fluorouracil (a widely used cytotoxic drug) and further metabolized to fluorinated ribo- and deoxyribonucleotides. Inhibits DNA and RNA synthesis and interfers with ribosomal protein synthesis. Displays antifungal and antitumor activity. Lately with the development of gene therapy, it has been introduced as a prodrug in combination with the cytosine deaminase suicide gene as antitumor compound, significantly improving survival and reducing tumor size in selected tumors.
Keywords: 4-Amino-5-fluoro-2(1H)-pyrimidinone, Flucytosine, NSC 103805, Ancotil, 5-FC, Ancobon, Ro 2-9915
Supplier: Chemodex
Supplier-Nr: F0077

Properties

Application: Antifungal, Antitumor
MW: 129,09 D
Formula: C4H4FN3O
Purity: >99%
Format: Solid

Database Information

CAS : 2022-85-7| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
GHS Hazard Pictograms:
H Phrases: H361
P Phrases: P281
Caution
Our products are for laboratory research use only: Not for administration to humans!
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