4-Thiouracil

4-Thiouracil
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16952-500 500 mg -

6 - 10 business days*

74.00€
Cay16952-1 1 g -

6 - 10 business days*

121.00€
Cay16952-5 5 g -

6 - 10 business days*

526.00€
 
4-Thiouracil is a site-specific, photoactivatable probe used to detect RNA structures and nucleic... more
Product information "4-Thiouracil"
4-Thiouracil is a site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts. It absorbs ultraviolet light >300 nm and, in the presence of oxygen, acts as an energy donor to produce singlet oxygen by triplet-triplet energy transfer. The highly reactive oxygen species then reacts readily with 4-thiouracil, leading to the production of uracil and uracil-6-sulfonate, which is fluorescent at a wavelength of ~390 nm. 4-Thiouracil is used as a T. gondii uracil phosphoribosyltransferase substrate to produce 4-thiouridine monophosphate, which can ultimately be incorporated into RNA.Formal Name: 3,4-dihydro-4-thioxo-2(1H)-pyrimidinone. CAS Number: 591-28-6. Synonyms: 2-hydroxy-4-Mercaptopyrimidine, NSC 43288, 4-Thiopyrimidin-2-one, 4-TU. Molecular Formula: C4H4N2OS. Formula Weight: 128.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.5 mg/ml, DMSO: 10 mg/ml, Ethanol: 1 mg/ml. lambdamax: 246, 326 nm. SMILES: O=C(NC=C1)NC1=S. InChi Code: InChI=1S/C4H4N2OS/c7-4-5-2-1-3(8)6-4/h1-2H,(H2,5,6,7,8). InChi Key: OVONXEQGWXGFJD-UHFFFAOYSA-N.
Keywords: 2-hydroxy-4-Mercaptopyrimidine, 4-Thiopyrimidin-2-one, 4-TU, NSC 43288, 3,4-dihydro-4-thioxo-2(1H)-pyrimidinone
Supplier: Cayman Chemical
Supplier-Nr: 16952

Properties

Application: Photoactivatable RNA probe
MW: 128.1 D
Formula: C4H4N2OS
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 591-28-6| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H312, H332
P Phrases: P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P361+P364, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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