4'-O-Methylresveratrol

4'-O-Methylresveratrol is a stilbene that has been found in Rumex and has diverse biological activities. It inhibits growth of A549, SKOV3, SK-MEL-2, XF498, and HCT15 cancer cells (IC50s = 3.8, 5.7, 3.2, 5.6, and 6.7 µg/ml, respectively). 4'-O-Methylresveratrol (0.05-0.2 mM) inhibits rabbit platelet aggregation induced by collagen or arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It scavenges free radicals in a Trolox equivalent antioxidant capacity (TEAC) assay. 4'-O-Methyresveratrol suppresses RANKL-induced osteoclastic differentiation of murine bone marrow-derived macrophages (BMDMs) and reduces LPS-induced bone loss in mice when administered at a dose of 50 mg/kg.Formal Name: 5-[(1E )-2-(4-methoxyphenyl)ethenyl]-1,3-benzenediol. CAS Number: 33626-08-3. Synonyms: Deoxyrhapontigenin, trans-3,5-Dihydroxy-4'-methoxystilbene, 4-Methoxyresveratrol. Molecular Formula: C15H14O3. Formula Weight: 242.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml, DMSO: 25 mg/ml, Ethanol: 10 mg/ml. lambdamax: 216, 305, 319 nm. SMILES: OC1=CC(O)=CC(/C=C/C2=CC=C(OC)C=C2)=C1. InChi Code: InChI=1S/C15H14O3/c1-18-15-6-4-11(5-7-15)2-3-12-8-13(16)10-14(17)9-12/h2-10,16-17H,1H3/b3-2+. InChi Key: IHVRWFJGOIWMGC-NSCUHMNNSA-N. Origin: Synthetic.