4-Fluoro-L-phenylalanine

4-Fluoro-L-phenylalanine is a non-proteinogenic amino acid and an inhibitor of protein synthesis. It inhibits growth of MCF-7 breast cancer cells (IC50 = 11.8 µM). 4-Fluoro-L-phenylalanine reversibly inhibits stomatin-induced T. vorax macrostomal differentiation in a concentration-dependent manner. It has been used to replace phenylalanine residues in polypeptides for determining site-specific solvent accessibility by 19F-NMR.CAS Number: 1132-68-9. Synonyms: 4F-Phe, L-para-Fluorophenylalanine, para-Fluoro-L-phenylalanine. Molecular Formula: C9H10FNO2. Formula Weight: 183.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 5 mg/ml. SMILES: FC1=CC=C(C[C@H](N)C(O)=O)C=C1. InChi Code: InChI=1S/C9H10FNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1. InChi Key: XWHHYOYVRVGJJY-QMMMGPOBSA-N.