3-hydroxy-3-Methylglutaric anhydride

The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase mediates the rate-limiting step in cholesterol synthesis, converting HMG-CoA to mevalonate. 3-hydroxy-3-Methylglutaric anhydride is a precursor that is used in the synthesis of HMG-CoA. It has also been used in the synthesis of 3-alkyl-3-hydroxyglutaric acids that act as inhibitors of HMG-CoA reductase.Formal Name: dihydro-4-hydroxy-4-methyl-2H-pyran-2,6(3H)-dione. CAS Number: 34695-32-4. Synonyms: Dicrotalic anhydride, HMG anhydride. Molecular Formula: C6H8O4. Formula Weight: 144.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 218 nm. SMILES: O=C(CC(C)(O)C1)OC1=O. InChi Code: InChI=1S/C6H8O4/c1-6(9)2-4(7)10-5(8)3-6/h9H,2-3H2,1H3. InChi Key: UWOCHZAKVUAJQJ-UHFFFAOYSA-N.