2'-Deoxyadenosine-5'-O-triphosphate (sodium salt hydrate)

2'-Deoxyadenosine-5'-O-triphosphate (sodium salt hydrate)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay32566-25 25 mg -

6 - 10 business days*

94.00€
Cay32566-50 50 mg -

6 - 10 business days*

166.00€
Cay32566-100 100 mg -

6 - 10 business days*

313.00€
Cay32566-250 250 mg -

6 - 10 business days*

642.00€
 
2'-Deoxyadenosine-5'-O-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic... more
Product information "2'-Deoxyadenosine-5'-O-triphosphate (sodium salt hydrate)"
2'-Deoxyadenosine-5'-O-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate (Cay-14498). dATP is a substrate for DNA polymerase in the synthesis of DNA. It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis. dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications. dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations in the gene for adenosine deaminase, the enzyme that catalyzes the deamination of adenosine and deoxyadenosine.Formal Name: ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate, trisodium salt, hydrate. Synonyms: dATP. Molecular Formula: C10H13N5O12P3 . 3Na [XH2O]. Formula Weight: 557.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 259 nm. SMILES: NC1=NC=NC2=C1N=CN2[C@@]3([H])C[C@H](O)[C@@H](COP(OP(OP(O)([O-])=O)([O-])=O)([O-])=O)O3.[Na+].[Na+].[Na+].O. InChi Code: InChI=1S/C10H16N5O12P3.3Na.H2O/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19,,,,/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19),,,,1H2/q,3*+1,/p-3/t5-,6+,7+,,,,/m0..../s1. InChi Key: RQGMMLFBAUODIH-YYWCTZDQSA-K.
Keywords: ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate, trisodium salt, hydrate
Supplier: Cayman Chemical
Supplier-Nr: 32566

Properties

Application: Purine nucleotide, DNA polymerase substrate, noncompetitive ribonucleotide reductase inhibitor
MW: 557.1 D
Formula: C10H13N5O12P3 . 3Na [XH2O]
Purity: >95%
Format: Crystalline Solid

Database Information

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "2'-Deoxyadenosine-5'-O-triphosphate (sodium salt hydrate)"
Write a review
or to review a product.
Viewed