2-cyano-Pyrimidine

2-cyano-Pyrimidine
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10007121-500 500 mg -

6 - 10 business days*

9.00€
Cay10007121-1 1 g -

6 - 10 business days*

18.00€
Cay10007121-5 5 g -

6 - 10 business days*

79.00€
Cay10007121-10 10 g -

6 - 10 business days*

140.00€
 
Cathepsin K is a lysosomal cysteine protease found in osteoclasts whose elevated activity has... more
Product information "2-cyano-Pyrimidine"
Cathepsin K is a lysosomal cysteine protease found in osteoclasts whose elevated activity has been linked to the formation of osteoporosis and arthritis. 2-cyano-Pyrimidine is a cathepsin K inhibitor whose basic structure and derivatives are being studied for the treatment of osteoporosis. 2-cyano-Pyrimidine has an IC50 value of 170 nM for inhibition of cathepsin K. Formal Name: 2-pyrimidinecarbonitrile. CAS Number: 14080-23-0. Molecular Formula: C5H3N3. Formula Weight: 105.1. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 20 mg/ml, PBS (pH 7.2): 3 mg/ml. lambdamax: 213, 254 nm. SMILES: NCc1ncccn1. InChi Code: InChI=1S/C5H3N3/c6-4-5-7-2-1-3-8-5/h1-3H. InChi Key: IIHQNAXFIODVDU-UHFFFAOYSA-N.
Keywords: 2-pyrimidinecarbonitrile
Supplier: Cayman Chemical
Supplier-Nr: 10007121

Properties

Application: Cathepsin K inhibitor
MW: 105.1 D
Formula: C5H3N3
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 14080-23-0| Find alternatives
KEGG ID : K01371 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301, H317
P Phrases: P261, P264, P270, P272, P280, P301+310, P302+352, P321, P330, P333+313, P362+364, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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