1-Deoxynojirimycin

1-Deoxynojirimycin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay21500-5 5 mg -

6 - 10 business days*

84.00€
Cay21500-10 10 mg -

6 - 10 business days*

146.00€
Cay21500-25 25 mg -

6 - 10 business days*

302.00€
Cay21500-50 50 mg -

6 - 10 business days*

562.00€
 
1-Deoxynojirimycin (1-DNJ) is an iminosugar that has been found in M. alba (mulberry) leaves and... more
Product information "1-Deoxynojirimycin"
1-Deoxynojirimycin (1-DNJ) is an iminosugar that has been found in M. alba (mulberry) leaves and has diverse biological activities. It inhibits the activities of alpha- and beta-glucosidase (IC50s = 35 and 71 µM, respectively). 1-DNJ (5 mM) reduces the formation of N-linked complex oligosaccharides in IEC-6 cells. It inhibits HIV-1 envelope-mediated membrane fusion in CEM cells when used at a concentration of 2 mM. 1-DNJ (1-100 µg/ml) reduces the invasion and migration of B16/F10 mouse melanoma cells. It improves glucose and insulin tolerance in db/db mice when administered intravenously at doses ranging from 20 to 80 mg/kg per day for four weeks.Formal Name: 2R-(hydroxymethyl)-3R,4R,5S-piperidinetriol. CAS Number: 19130-96-2. Synonyms: BAY-h-5955, D-1-Deoxynojirimycin, 1-DNJ, 1-dNM, Moranoline. Molecular Formula: C6H13NO4. Formula Weight: 163.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 10 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O[C@H]1[C@H](O)[C@@H](O)CN[C@@H]1CO. InChi Code: InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1. InChi Key: LXBIFEVIBLOUGU-JGWLITMVSA-N.
Keywords: 1-dNM, BAY-h-5955, D-1-Deoxynojirimycin, Moranoline, 2R-(hydroxymethyl)-3R,4R,5S-piperidinetriol
Supplier: Cayman Chemical
Supplier-Nr: 21500

Properties

Application: alpha-?glucosidase inhibitor
MW: 163.2 D
Formula: C6H13NO4
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 19130-96-2| Matching products
KEGG ID : K05546 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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