1-(4-Chlorobenzhydryl)piperazine

1-(4-Chlorobenzhydryl)piperazine is an inactive metabolite of meclizine (Cay-14615) and chlorcyclizine (Cay-19239). It has also been found as an impurity in commercial preparations of hydroxyzine (Cay-24039) and cetirizine (Cay-19686). 1-(4-Chlorobenzhydryl)piperazine has been used in the synthesis of voltage-gated sodium channel 1.7 (Nav1.7) inhibitors, anticancer agents, and antihistamines.Formal Name: 1-[(4-chlorophenyl)phenylmethyl]-piperazine. CAS Number: 303-26-4. Synonyms: N-(p-Chlorobenzhydryl)-piperazine, Norchlorcyclizine, NSC 86164. Molecular Formula: C17H19ClN2. Formula Weight: 286.8. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml, Ethanol: 25 mg/ml. lambdamax: 231 nm. SMILES: ClC1=CC=C(C(N2CCNCC2)C3=CC=CC=C3)C=C1. InChi Code: InChI=1S/C17H19ClN2/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20/h1-9,17,19H,10-13H2. InChi Key: UZKBSZSTDQSMDR-UHFFFAOYSA-N.