1,3,7-Trimethyluric Acid-d9

1,3,7-Trimethyluric acid-d9 is intended for use as an internal standard for the quantification of 1,3,7-trimethyluric acid (Cay-16949) by GC- or LC-MS. 1,3,7-Trimethyluric acid is a derivative of uric acid (Cay-16219) and a metabolite of caffeine (Cay-14118). It is formed from caffeine by the cytochrome P450 (CYP) isoform CYP3A4. 1,3,7-Trimethyluric acid (500 µM) scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes.Formal Name: 7,9-dihydro-1,3,7-tri(methyl-d3)-1H-purine-2,6,8(3H)-trione. CAS Number: 117490-42-3. Synonyms: TMU-d9, 8-oxo Caffeine-d9. Molecular Formula: C8HD9N4O3. Formula Weight: 219.2. Purity: >99% deuterated forms (d1-d9). Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 1 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 236, 290 nm. SMILES: O=C(N(C1=O)C([2H])([2H])[2H])C(N(C(N2)=O)C([2H])([2H])[2H])=C2N1C([2H])([2H])[2H]. InChi Code: InChI=1S/C8H10N4O3/c1-10-4-5(9-7(10)14)11(2)8(15)12(3)6(4)13/h1-3H3,(H,9,14)/i1D3,2D3,3D3. InChi Key: BYXCFUMGEBZDDI-GQALSZNTSA-N.