1,2-Dioleoyl-3-dimethylammonium-propane

1,2-Dioleoyl-3-dimethylammonium-propane (DODAP) is an ionizable cationic lipid (pKa = 5.59 in a TNS binding assay). It has been used as a component in liposomes that can be used to encapsulate siRNA, immunostimulatory oligodeoxynucleotides, antisense oligonucleotides, or chemotherapeutic agents for in vitro and in vivo delivery.Formal Name: 9Z-octadecenoic acid, 1,1'-[1-[(dimethylamino)methyl]-1,2-ethanediyl] ester. CAS Number: 127512-29-2. Synonyms: 18:1 DAP, DODAP. Molecular Formula: C41H77NO4. Formula Weight: 648.1. Purity: >98%. Formulation: (Request formulation change), An oil. Solubility: Chloroform: Slightly Soluble, Methanol: Slightly Soluble. SMILES: O=C(CCCCCCC/C=C\CCCCCCCC)OCC(CN(C)C)OC(CCCCCCC/C=C\CCCCCCCC)=O. InChi Code: InChI=1S/C41H77NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(43)45-38-39(37-42(3)4)46-41(44)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h19-22,39H,5-18,23-38H2,1-4H3/b21-19-,22-20-. InChi Key: NYDLOCKCVISJKK-WRBBJXAJSA-N.