1,2-Diheptanoyl-sn-glycero-3-PC

1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions. It is commonly used in the formation of lipid bilayers and mixed micelles that has a critical micelle concentration (CMC) of 1.6 mM. Short-chain phospholipids, such as DHPC-C7 and 1,2-dihexanoyl-sn-glycero-PC (DHPC-C6, Cay-25585), increase the formation rate of substrate-supported planar phospholipid bilayers on glass and silica. DHPC-C7 inhibits insulin fibril formation in vitro in a concentration-dependent manner and inhibits cytotoxicity induced by insulin fibril formation in PC12 and SH-SY5Y cells when used at concentrations ranging from 0.5 to 4 mM.Formal Name: (7R)-4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxoheptyl)oxy]-3,5,9-trioxa-4-phosphahexadecan-1-aminium, inner salt, 4-oxide. CAS Number: 39036-04-9. Synonyms: DHPC-C7, di-C7-PC. Molecular Formula: C22H44NO8P. Formula Weight: 481.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: > 20 mg/ml, DMSO: > 7 mg/ml, Ethanol: > 30 mg/ml, PBS (pH 7.2): > 250 µg/ml. lambdamax: 210 nm. SMILES: [O-]P(OC[C@H](OC(CCCCCC)=O)COC(CCCCCC)=O)(OCC[N+](C)(C)C)=O. InChi Code: InChI=1S/C22H44NO8P/c1-6-8-10-12-14-21(24)28-18-20(31-22(25)15-13-11-9-7-2)19-30-32(26,27)29-17-16-23(3,4)5/h20H,6-19H2,1-5H3/t20-/m1/s1. InChi Key: RBFSPQDASPEAID-HXUWFJFHSA-N. Side Chain Carbon Sum: 14:0.