Narasin (sodium salt)

Narasin is an ionophore antibiotic isolated from certain Streptomyces sp. and used in veterinary practice as a coccidiostat for gastrointestinal parasites. It has also been shown to inhibit NF-kappaB signaling via inhibition of IkappaBalpha phosphorylation (IC50 = 3.2 µM) and to stimulate tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis in glioma cells via ER stress.Formal Name: 4S-methyl-salinomycin, monosodium salt. CAS Number: 58331-17-2. Synonyms: 4-Methylsalinomycin, Monteban, Narasin A. Molecular Formula: C43H71O11 . Na. Formula Weight: 787.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: Soluble, DMSO: Soluble, Ethanol: Soluble, Methanol: Soluble. SMILES: C[C@@H]1[C@@]([C@@H](C)[C@H](O)[C@H](C)C([C@@H]([C@]2([H])[C@@H](C)C[C@@H](C)[C@]3(O[C@@]4(CC[C@]([C@@]5([H])CC[C@@](CC)(O)[C@H](C)O5)(C)O4)[C@H](O)C=C3)O2)CC)=O)([H])O[C@]([C@@H](CC)C([O-])=O)([H])[C@@H](C)C1.[Na+]. InChi Code: InChI=1S/C43H72O11.Na/c1-12-30(35(46)27(8)34(45)28(9)36-23(4)21-24(5)37(51-36)31(13-2)39(47)48)38-25(6)22-26(7)42(52-38)18-15-32(44)43(54-42)20-19-40(11,53-43)33-16-17-41(49,14-3)29(10)50-33,/h15,18,23-34,36-38,44-45,49H,12-14,16-17,19-22H2,1-11H3,(H. InChi Key: NBRZEFXQRCTYMC-DAALJYCPSA-M.