MRSA Antibiotic 1

MRSA antibiotic 1 is an antibiotic. It is active against S. aureus, methicillin-resistant S. aureus (MRSA), and B. subtilis (MICs = 2, 4, and 2 µg/ml, respectively) without inducing cytotoxicity in HepG2, HSkMC, or IMR-90 cells at 10 µM. MRSA antibiotic 1 is also active against 40 antibiotic-resistant clinical isolates (median MICs = 2-16 µg/ml). It decreases MRSA viral titers in the skin in a neutropenic mouse wound infection model when applied topically at 1% (w/w), as well as reduces MRSA viral titers in the thigh in a neutropenic mouse thigh infection model when administered intraperitoneally at 80 mg/kg.Formal Name: 4-chloro-2-[[2-(2,4-dichlorophenoxy)acetyl]amino]-benzoic acid. CAS Number: 667410-81-3. Molecular Formula: C15H10Cl3NO4. Formula Weight: 374.6. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Sparingly soluble: 1-10 mg/ml. SMILES: ClC1=CC(NC(COC2=CC=C(Cl)C=C2Cl)=O)=C(C=C1)C(O)=O. InChi Code: InChI=1S/C15H10Cl3NO4/c16-8-2-4-13(11(18)5-8)23-7-14(20)19-12-6-9(17)1-3-10(12)15(21)22/h1-6H,7H2,(H,19,20)(H,21,22). InChi Key: KKKPLTVKYNLFCJ-UHFFFAOYSA-N.