Marbofloxacin

Marbofloxacin is a broad-spectrum fluoroquinolone antibiotic active against Gram-negative, Gram-positive and Mycoplasma spp. bacteria. It acts by inhibiting the activity of DNA gyrase and topoisomerase IV, enzymes fundamental to the replication and transcription of bacterial DNA. Thus, the inhibition of these enzymes leads to the death of the bacteria. Marbofloxacin has also been shown to exhibit antileishmanial activity in a canine model. Marbofloxacin has low toxicity and limited development of bacterial resistance. Compound can be used as analytical reference material.