Drimentine B

Drimentine B is a terpenylated diketopiperazine originally isolated from Actinomycete bacteria that has anticancer activity. It inhibits the proliferation of NS-1 murine beta lymphocyte myeloma cells by 41 and 59% in vitro when used at concentrations of 50 and 100 µg/ml, respectively.Formal Name: (5aS,6aS,11aS)-6a-[[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methyl]-6,6a,11,11a-tetrahydro-3H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,13(2H,5aH)-dione. CAS Number: 204398-91-4. Molecular Formula: C31H39N3O2. Formula Weight: 485.7. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: soluble, DMSO: soluble, Ethanol: soluble, Methanol: soluble. SMILES: O=C([C@@](C[C@]1(C[C@@]2([H])C(CC[C@]3([H])[C@]2(C)CCCC3(C)C)=C)[C@@]4([H])NC5=C1C=CC=C5)([H])N4C6=O)N7C6=CCC7. InChi Code: InChI=1S/C31H39N3O2/c1-19-12-13-25-29(2,3)14-8-15-30(25,4)21(19)17-31-18-24-26(35)33-16-7-11-23(33)27(36)34(24)28(31)32-22-10-6-5-9-20(22)31/h5-6,9-11,21,24-25,28,32H,1,7-8,12-18H2,2-4H3/t21-,24-,25-,28-,30+,31-/m0/s1. InChi Key: SUUCBHITXBJOGT-JMGSXGSMSA-N.