Difloxacin (hydrochloride)

Difloxacin is a fluoroquinolone antibiotic. It is active against isolates of anaerobic bacteria, including B. fragilis, as well as Fusobacterium and Actinomyces species with MIC values ranging from =0.125 to 8 µg/ml. It eliminates E. coli and B. fragilis infection in a rat intra-abdominal abscess model when administered at a dose of 40 mg/kg three times per day.Formal Name: 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride. CAS Number: 91296-86-5. Synonyms: A-56619. Molecular Formula: C21H19F2N3O3 . HCl. Formula Weight: 435.9. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. lambdamax: 281, 319, 332 nm. SMILES: OC(C1=CN(C2=CC=C(F)C=C2)C3=CC(N4CCN(C)CC4)=C(F)C=C3C1=O)=O.Cl. InChi Code: InChI=1S/C21H19F2N3O3.ClH/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14,/h2-5,10-12H,6-9H2,1H3,(H,28,29),1H. InChi Key: JFMGBGLSDVIOHL-UHFFFAOYSA-N.